Palermo is considered one of the most important ports in the Mediterranean. The port of Palermo offers year-round connections with Naples, Civitavecchia, Livorno, Genoa, Salerno, Ustica and the Aeolian Islands.

Trapani is the main port to visit the Aegadian Islands and Pantelleria.

Infact, the ports of the Egadi Islands, Favignana, Marsala, Levanzo and Marettimo are all connected to to the port of Trapani.

Other ports in Sicily are: Messina, Termini Imerese, Milazzo, the Aeolian Islands and the port of Pozzallo (south of Ragusa). From Pozzallo there are ferries from/to Malta. For Malta, there are: Ferries Catania – Malta and Ferries Palermo – Malta